Stabilized R-Lipoic Acid

Frequently Asked Questions

1) What is Stabilized R-Lipoic Acid?

Stabilized R-lipoic acid is a sodium salt form of R-lipoic acid and, unlike pure R-Lipoic acid, the sodium (or potassium salt) form is a stable form of R-lipoic acid that will not degrade at high temperatures (a process known as "polymerization"). Additionally, Stabilized R-lipoic acid is significantly more bioavailable (readily absorbed by the body) than both R-lipoic acid or standard alpha lipoic acid, and does not contain any solvent residues.

Lipoic acid occurs in two forms that are respectively designated as "R" and "S". Studies suggest that R-lipoic acid (the natural form), is more biologically active than the S form.

2) Of what benefit is Stabilized R-Lipoic Acid to my health?

Lipoic acid affords a vast amount of positive health benefits that includes, but is not limited to: improvements in blood pressure, insulin resistance, lipid profile, weight maintenance, insulin sensitivity, diabetic neuropathy, protection against cataract formation, improvements in visual function in glaucoma, retinal cell death prevention when combined with vitamin E in retinitis pigmentosa, reduction of post-stroke brain damage, bone loss mitigation, the removal of toxic metals from the body, a reduction in both the frequency and intensity of migraines, and improvement in skin texture.

Lipoic acid plays an important role in both glucose metabolism and energy production. Because it is both fat and water-soluble, lipoic acid is often referred to as the "universal antioxidant." Due to this unique quality, lipoic acid is easily absorbed into the bloodstream and is transported into many organs and systems within the body such as the brain, liver, and nerves. In contrast, vitamin C is not very lipid-soluble, which makes it difficult for that particular antioxidant to penetrate the lipid wall of cell membranes. Similarly, yet in contrast to vitamin C, vitamin E, another well-known antioxidant, fails in the water-solubility department. However, studies have shown that when lipoic acid is combined with these particular antioxidants, the body's ability to fight free radicals is greatly augmented. In fact, lipoic acid has been found to assist in the regeneration of both vitamins C and E.

Furthermore, lipoic acid assists in amplifying the positive effects of other important antioxidants in the body such as glutathione and coenzyme Q10. It has been shown to also "team up" with the B-vitamin family to support energy production in the body by converting the various components of the food that we consume on a daily basis (such as carbohydrates, proteins, and fats) into stored energy for future use. Lipoic acid does this by helping to protect mitochondria, the energy-producing factories of cells, from being damaged by oxidative stress. This "damage control" measure ensures that energy production in the body remains efficient.

3) What separates this form of Stabilized R-Lipoic Acid from other brands?


All stabilized R-Lipoic acid sold on the market is purchased wholesale from the same source (GeroNova Research). However, forms that are not stabilized should be avoided, as they degrade very quickly and lack the necessary efficacy to obtain noticeable improvements in health.

4) Theoretically speaking, how can Stabilized R-Lipoic Acid potentially benefit my hair?

Lipoic acid plays a protective role during conditions of elevated glucose levels, which are highly detrimental to both your health and hair. Lipoic acid boosts mitochondrial production of the highly beneficial Superoxide Dismutase (SOD), and serves as a protectant against decreased microvascular profusion, which would otherwise deprive oxygen transport along tiny endothelial passages. In addition, lipoic acid engenders improved liver and kidney health, which indirectly positively influences hair.

5) Does Stabilized R-Lipic Acid offer any exercise benefits?

The combination of exercise training, and antioxidant treatment using lipoic acid in an animal model of obesity-associated insulin resistance, has demonstrated a unique interactive effect that was shown to result in a greater improvement in insulin action on skeletal muscle glucose transport than either intervention individually. Moreover, this interactive effect of exercise training and lipoic acid is due in part to improvements in IRS-1-dependent insulin signaling. This research highlights the effectiveness of combining endurance exercise training along with antioxidants in beneficially modulating the molecular defects in insulin action observed in insulin-resistant skeletal muscle.

6) Any potential side-effects to consider?

If sensitive to changes in blood sugar, or if you are being treated for diabetes with drugs that are designed to lower blood sugar levels, then it is recommended that you first consult with your physician prior to supplementing with stabilized R-lipoic acid. The most common side-effect observed is hypoglycemia. If this occurs, it is recommend that you use alpha lipoic acid instead. In general, lipoic acid side-effects are rare, which includes skin allergy and gastrointestinal disturbances.

If erring on the side of caution, start with consuming one pill a day for the first few weeks, before then increasing the dosage (if well-tolerated) to two pills for a month, and then three per day as recommended on the product label.